


23 cases received a placebo and 3 of these had a positive outcome.

In this example, in a first study 73 cases were treated with an active substance and of these, 15 had a positive outcome. The data of different studies can be entered as follows in the spreadsheet: Next the heterogeneity statistic is incorporated to calculate the summary odds ratio under the random effects model (DerSimonian & Laird, 1986). MedCalc uses the Mantel-Haenszel method (Mantel & Haenszel, 1959) for calculating the weighted pooled odds ratio under the fixed effects model. For a short overview of meta-analysis in MedCalc, see Meta-analysis: introduction.
